Thiotepa pubchem

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August undefined, 2024

WebNov 1, 2024 · Thiotepa for injection is a cytotoxic drug. Follow applicable special handling and disposal procedures 1. Reconstitution Reconstitute Thiotepa for injection 15 mg with 1.5 ml of sterile water for injection. Using a syringe fitted with a needle, aseptically withdraw 1.5 ml of sterile water for injection. WebNCATS Inxight Drugs — THIOTEPA ... Chemical

Thiotepa: Uses, Interactions, Mechanism of Action

WebJan 4, 2024 · Thiotepa is a cytotoxic agent of the polyfunctional type, related chemically and pharmacologically to nitrogen mustard. The radiomimetic action of thiotepa is believed to occur through the release … WebN,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. greg slaughter b league

DRUG NAME: Thiotepa - BC Cancer

WebThio-TEPA, N,N′,N″-Triethylenethiophosphoramide, Thio-Tep, Thiofozil, Thiotef, Tio-tef, Tiofosfamid, Tiofosyl, Tiofozil, Tris(aziridinyl)phosphine sulfide Empirical Formula (Hill Notation): C6H12N3PS CAS Number: 52-24-4 Molecular Weight: 189.22 MDL number: MFCD00145452 PubChem Substance ID: 329751312 NACRES: NA.24 Recommended … WebA typical direct side effect of thiotepa suppressing the bone marrow is an increased risk of anemia, bleeding, and infection. In rare cases, thiotepa and other alkylating agents can trigger the blood cancer leukemia. The risk of developing leukemia peaks about 5 to 10 years after receiving thiotepa. WebThioTEPA is used a as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases in adult and paediatric patients. Also, when high dose chemotherapy with HPCT support it is appropriate for the treatment of solid tumours in adult and paediatric patients. Mode of … fiche bmf

Thiotepa (Thioplex®, Tepadina®) OncoLink

WebThiotepa is used as intravesical chemotherapy in bladder cancer. [7] It may be used prophylactically to prevent seeding of tumor cells at cystoscopic biopsy; as an adjunctive agent at the time of biopsy; or as a therapeutic agent to prevent recurrence after cystoscopic resection of bladder tumor ( transurethral resection of bladder tumor , TURBT). WebNov 1, 2024 · The recommended dose of Thiotepa for injection for treatment of adenocarcinoma of the breast or ovary is 0.3 to 0.4 mg/kg intravenously. Doses should be … fiche bmoWebN,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- … gregs lawn mower repairdanvillepa

"WebAACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB. ... N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the … " - Thiotepa pubchem

Thiotepa pubchem

WebOverview. N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer.It is also used as conditioning for Bone marrow transplantation. WebSep 12, 2024 · Thiotepa (thye' oh tep' a) is an ethylenimine similar in structure and activity to altretamine and is believed to act as an alkylating agent. The alkylating agents act by causing modification and cross linking …

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Webthiotepa, idecabtagene vicleucel. Either increases effects of the other by immunosuppressive effects; risk of infection. Avoid or Use Alternate Drug. influenza virus … WebAACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB. ... N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N’,N’’- triethylenephosphoramide (TEPA). The radiomimetic action of thiotepa is ...

WebThiotepa may be given rapidly intravenously in doses of 0.3–0.4 mg/kg at intervals of 1–4 weeks. The drug has also been given intravenously in doses of 0.2 mg/kg or 6 mg/m 2 daily for 4 or 5 days at intervals of 2–4 weeks. … WebSep 15, 2024 · The invention relates to novel compositions, combinations and methods relating to compounds which inhibit EZH2 and their uses for treating and/or preventing tumors associated with methyltransferase EZH2. More specifically the invention relates to synergistic bi-therapy compositions for use in a method of treating and/or preventing …

WebThioTEPA is used a as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases in … WebJul 16, 2024 · Thiotepa can be given in several ways, including: into a vein (intravenous), into the bladder (intravesicular), into the spinal fluid (intrathecal), and into the abdominal cavity (intraperitoneal). The dose is dependent on your size, the method of administration, and the type of cancer being treated.

WebSynonym (s): Thio-TEPA, N,N′,N″-Triethylenethiophosphoramide, Thio-Tep, Thiofozil, Thiotef, Tio-tef, Tiofosfamid, Tiofosyl, Tiofozil, Tris (aziridinyl)phosphine sulfide Empirical Formula (Hill Notation): C6H12N3PS CAS Number: 52-24-4 Molecular Weight: 189.22 MDL number: MFCD00145452 PubChem Substance ID: 329751312 NACRES: NA.24

fiche bloc alimentationWebThioTEPA ThioTEPA Systematic (IUPAC) name N,N ' N '-triethylenethiophosphoramide Identifiers CAS number 52-24-4 ATC code L01AC01 PubChem 5453 Chemical data. ... PubChem: 5453: Chemical data: Formula: C 6 H 12 N 3 P S : Mol. mass: 189.219 g/mol Pharmacokinetic data: Bioavailability ? Metabolism: Hepatic (CYP2B6, CYP2C11) Half life : greg sisson exp realtyWebMae ThioTEPA (INN, enw cemegol: N,N′,N″-triethylenethioffosfforamid) yn gyfrwng alcyleiddio a ddefnyddir i drin canser. [1] Y fformiwla cemegol ar gyfer y cyffur hwn yw C₆H₁₂N₃PS. Mae thiotepa yn gynhwysyn actif yn Tepadina. Defnydd meddygol [ golygu golygu cod y dudalen] greg sloan chipleyWebTHIOTEPA UNII: 905Z5W3GKH Formula: C6H12N3PS Preferred Substance Name: THIOTEPA InChIKey: FOCVUCIESVLUNU-UHFFFAOYSA-N Synonyms and Mappings 52-24-4 200-135-7 1,1',1''-PHOSPHINOTHIOYLIDYNETRIS... fiche bnqWebThiotepa is approved to treat: Bladder cancer. Breast cancer. Malignant pleural effusion, malignant pericardial effusion, and malignant peritoneal effusion. Ovarian cancer. … fiche bnbWebFeb 16, 2024 · Thiotepa Riemser is indicated, in combination with other chemotherapy medicinal products: with or without total body irradiation (TBI), as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases in adult and paediatric patients; fiche bniWebThiotepa is approved to treat: Bladder cancer. Breast cancer. Malignant pleural effusion, malignant pericardial effusion, and malignant peritoneal effusion. Ovarian cancer. Thiotepa is also being studied in the treatment of other types of cancer and as part of a regimen to prepare patients for bone marrow and stem cell transplants. greg slaughter photography