Web031779 B6;CBA-Tg(Cyp19a1-cre)1Dlc/J Cyp19a1-Cre BAC transgenic mice express cre recombinase from the mouse Cyp19a1 (aromatase) promoter, faithfully recapitulating … WebAug 1, 2014 · For the Cyp19-Cre allele, female double heterozygotes ( Cited2∆LacZ/+ Cre+) were mated with Cited2flox/flox males, generating three control genotypes: Cited2+/flox Cre-; Cited2+/flox Cre+; Cited2∆LacZ/flox Cre-; and the conditionally deleted genotype Cited2∆LacZ/flox Cre+.
Expression of Cre recombinase in early diploid trophoblast cells …
WebAug 31, 2024 · Conditional depletion of Nrg1 in ovarian granulosa cells (Kawashima et al., 2014) was achieved by crossing Cyp19-Cre mice (Fan et al., 2008) with Nrg1 flox/flox mice (Yang et al., ... (Nrg1 flox/flox, WT and … WebMar 1, 2024 · Furthermore, behavioral abnormalities and cerebellar neuropathologies observed in MIA control offspring are prevented in Cyp19-Cre +;Il6ra fl/fl offspring. Our results demonstrate that IL-6 activation in placenta is required for relaying inflammatory signals to the fetal brain and impacting behaviors and neuropathologies relevant to ... birmingham tickets commonwealth games
The acceleration of reproductive aging in Nrg1flox/flox …
WebJun 14, 2024 · The differential ovarian phenotypes between the Foxl2-CRE;Yap1 flox/flox mice and Cyp19-CRE;Yap1 flox/flox mice may be attributed to the differential expression of Foxl2 and Cyp19 in granulosa cells. Because Foxl2 is predominantly expressed in granulosa cells of growing follicles, Foxl2 -driven deletion of Yap1 may affect follicle … WebThe Cyp19-Cre 5912 founder line specifically expresses Cre recom-binase at placental trophoblast precursor cells during the early stage of embryogenesis and shows minimal expression of Cre recombinase in fetal tissues (Wenzel and Leone, 2007), which WebWe conclude that the CYP19-Cre transgenic mouse developed here can be used in combination with conditional alleles to distinguish between embryonic and extra … birmingham thunderbolts softball