Brd2 compartmentalizes the accessible genome
WebMay 2, 2024 · Chen X, Shen Y, Draper W, Buenrostrol J D, Litzenburger U, Cho S W, Satpathy A, Carter A C, Ghosh R P, East-Seletsky A, Doudna J A, Greenleaf W J, Liphardt J T, Chang H Y. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nature Methods. 2016, 13(12):1013-1020. WebApr 11, 2024 · BRD2 facilitates mixing and compartmentalization of active chromatin upon cohesin depletion. BRD2’s function is counteracted by cohesin and BRD4. Liangqi Xie Peng Dong Zhe Liu Article 11 Apr...
Brd2 compartmentalizes the accessible genome
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WebApr 11, 2024 · BRD2 promotes mixing of accessible chromatin and active compartments, but BRD2 binding to chromatin as well as active compartment mixing is opposed by … WebHere, we show that the bromodomain and extraterminal (BET) family scaffold protein BRD2 promotes spatial mixing and compartmentalization of active chromatin after cohesin loss. …
WebPMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal … WebMar 31, 2016 · Fawn Creek Township is located in Kansas with a population of 1,618. Fawn Creek Township is in Montgomery County. Living in Fawn Creek Township offers …
WebBRD2 compartmentalizes the accessible genome Xie, L., Dong, P., Qi, Y., Hsieh, T. H. S., English, B. P., Jung, S. K., Chen, X., De Marzio, M., Casellas, R., Chang, H. Y., Zhang, B., Tjian, R. & Liu, Z., Apr 2024, In: Nature Genetics. 54, 4, p. 481-491 11 p. Research output: Contribution to journal › Article › peer-review cohesins Chromatin Genome WebMay 5, 2024 · BRD2 facilitates mixing and compartmentalization of active chromatin upon cohesin depletion. BRD2’s function is counteracted by cohesin and BRD4. Liangqi Xie Peng Dong Zhe Liu Article 11 Apr...
WebBRD2 compartmentalizes the accessible genome. Xie, Liangqi; Dong, Peng; Qi, Yifeng; Hsieh, Tsung-Han S. et al. Part of Nature Genetics, p. 481-491, 2024.. DOI for BRD2 compartmentalizes the accessible genome
Webby BRD2 Yubao Cheng1 and Siyuan Wang 1,2,3,4,5,6,7,8,* Themolecularmechanismunderly-ing 3D genome compartmentaliza-tion remains a mystery. Xie et al. found that the bromodomain and extraterminal (BET) family scaffold protein BRD2 promotes the com-partmentalization of the accessible chromatin domains after cohesin … summer house oyster white 5 drawer dresserWebApr 11, 2024 · Notably, genome compartmentalization mediated by BRD2 is antagonized on the one hand by cohesin and on the other hand by the BET homolog protein BRD4, … summer house on tonightWebDec 1, 2024 · Models chromatin compartmentalization by BRD2. Compartment A and B regions of chromatin are shown in red and blue, respectively. (A) The different functions of BRD2 and BRD4 in chromatin organization and transcription regulation. (B) Loop extrusion-dependent A–B compartment conversion upon BRD2 loss. paladin youth sportsWebBRD2 compartmentalizes the accessible genome ... Notably, genome compartmentalization mediated by BRD2 is antagonized on the one hand by cohesin and on the other hand by the BET homolog protein BRD4, both of which inhibit BRD2 binding to chromatin. Polymer simulation of our data supports a BRD2–cohesin interplay model of … summer house on halstedWebSeasonal Variation. Generally, the summers are pretty warm, the winters are mild, and the humidity is moderate. January is the coldest month, with average high temperatures … paladin wrath glyphsWebJul 7, 2024 · New mechanism of chromatin compartmentalization by BRD2. The molecular mechanism underlying 3D genome compartmentalization remains a mystery. Xie et al. found that the … summer house on music lane austin txWebHere, we show that the bromodomain and extraterminal (BET) family scaffold protein BRD2 promotes spatial mixing and compartmentalization of active chromatin after cohesin loss. … paladin youth football